EliA^TM on ImmunoCAP^TM 250

Automation and quality in autoimmunity testing

EliA^TM on ImmunoCAP^TM 250 ¨Cthe Future in Autoimmunity Testing ¨CNow!

High Throughput
¡ö 350 or more tests per day
¡ö additional throughput with over-night runs
¡ö results in one-minute intervals
¡ö continuous access for samples

Highly Automated
¡ö true walk-away
¡ö automatic „wake-up¡° and shut down
¡ö barcode reading for all reagents and samples to minimise errors
¡ö remote monitoring for easy troubleshooting
¡ö primary and secondary tubes accepted

Flexibility
¡ö patient-specific test profiles
¡ö autoimmunity and allergy in one run
¡ö small runs cost-efficient
¡ö priority function for urgent samples
¡ö reflex testing

Quality
¡ö accurate, standardised and reproducible results
¡ö custom-designed, reliable technology dedicated to antibody testing
¡ö reagents produced under GMP conditions
¡ö regular, system-specific quality control with Quality Club^TM EliA^TM Autoimmunity

The EliA^TM System

Time for the essentials
ImmunoCAP^TM 250 is a highly automated system for autoimmunity (EliA^TM) and allergy (ImmunoCAP^TM) testing. Designed to assist laboratory workflow by reducing hands-on time, it processes samples from test request to final result with minimal intervention.
Barcode identification of all reagents, mainframe worklist downloads or barcode/manual sample identification combine with on-board dilution to reduce manual handling and minimise errors.
Over-night runs with automatic shut down after the last sample and the automated „wake-up¡° give the option of increasing the available working hours of the instrument.
All reagents can be stored on board to minimise loading times.User-friendly operation makes test handling and data processing simple and convenient.

Cost efficient and flexible

The modular EliA^TM system allows for patient-specific, economical routine use. One standard curve is used for all analytes within a method and calibration is required only monthly. The calibration curve is generated and controlled as the instrument runs and raw data for calibrators, controls and patient samples is always accessible, making the entire process transparent and understandable for the user.
For every sample, an individual test panel can be compiled. Single samples can be run immediately and prioritised if the results are needed urgently and reflex testing from EliA^TM Symphony to specific ANA analytes is possible.
Wide measuring ranges and reproducible results optimise throughput and reduce the secondary-level testing required. To improve the efficiency of the laboratory, autoimmunity and allergy testing can be performed in the same run. The same-day result turnaround system provides the best possible service for clinicians and patients.

Intuitive, user friendly handling

The unique ImmunoCAP^TM Information Data Manager (IDM) software allows the integration of several ImmunoCAP^TM instruments (including ImmunoCAP^TM 100 and ImmunoCAP^TM 1000) into one network.
IDM manages all results, an in-depth quality control programme as well as the total laboratory stock. Additionally, IDM has a high-capacity patient database and allows a detailed documentation of results.
On the instrument itself, logical software accessed via a built-in touch screen, makes the handling of the system very easy.

Maximum specificity and sensitivity in autoimmunity testing

To ensure the highest quality of our autoantibody tests, it is crucial to use very pure, conformationally-correct antigens. We use human recombinant proteins and synthetic peptides whenever it increases antigenicity and thus sensitivity and specificity.
The polystyrene EliA^TMWells are pre-coated with defined antigens. In the testing process, sample material is pipetted into the EliATM well and specific autoantibodies present can bind to the antigen. This binding is detected by the addition of an enzyme-labelled conjugate followed by its substrate. The resulting fluorescence is detected by the built-in fluorometer and expressed in EliA^TM Units or International Units, where appropriate.

Automation for walk-away productivity

The ImmunoCAP^TM 250 system is highly automated, requiring minimal hands-on time.
A typical work-day schedule for EliA^TM on ImmunoCAP^TM 250 is shown below.

A boost in service for your laboratory and your clinicians

EliA^TM has been specifically designed to offer clinically relevant results in autoimmunity testing while meeting the laboratory demands of efficient and cost-effective workflow. As specialists in autoimmunity, we offer you all the benefits of our knowledge and experience through our high quality products and our technical and scientific support.

ImmunoCAP^TM 250

Technical Information

Size: 127 x 71 x 93 cm (w x d x h) table top
Weight: 220 kg
Power supply: 100, 120, 220, 230, 240 V / 50 - 60 Hz / 1.2 kVA
Environmental temperature: 18 - 32¡ãC
Data management: ImmunoCAP™ Information Data Manager (IDM), full feature PC connected
Operating system: Windows® 2000 / Windows® XP
Mainframe connection protocol: ASTM, MasterCAP^TM and Phamas
Clustering: optional
Solid and liquid waste handling: self contained or direct outlet connection
Samples: primary and secondary tubes; serum or plasma

EliA^TM Tests
           
                             Package size           Article No.
Celiac Disease
EliA™ Celikey® IgA Well      4 x 12 tests           14-5517-01
EliA™ Celikey® IgG Well      2 x 12 tests           14-5518-01
EliA™ Gliadin IgA Well       4 x 12 tests           14-5519-01

Rheumatoid Arthritis
EliA™ CCP Well               4 x 12 tests           14-5515-01

Connective Tissue Diseases
EliA™ dsDNA Well             4 x 12 tests           14-5500-01
EliA™ U1RNP Well             4 x 12 tests           14-5501-01
EliA™ RNP70 Well             4 x 12 tests           14-5511-01
EliA™ Sm Well                4 x 12 tests           14-5502-01
EliA™ Ro Well                4 x 12 tests           14-5503-01
EliA™ La Well                4 x 12 tests           14-5504-01
EliA™ CENP Well              2 x 12 tests           14-5505-01
EliA™ Scl-70 Well            2 x 12 tests           14-5506-01
EliA™ Jo-1 Well              2 x 12 tests           14-5507-01
EliA™ Symphony Well          4 x 12 tests           14-5508-01

Vasculitis / Goodpasture Syndrome
EliA™ PR3 Well              4 x 12 tests            14-5512-01
EliA™ MPO Well              4 x 12 tests            14-5513-01
EliA™ GBM Well              2 x 12 tests            14-5514-01

Phadia develops, manufactures and markets complete blood test systems to support the clinical diagnosis and monitoring of allergy, asthma and autoimmune diseases.

Besides strategic management, administration and business development, the international centre in Uppsala incorporates extensive research and development facilities, a state-of-the-art production plant and distribution system operating cost-effectively around the clock.

In Freiburg, Germany, a second centre develops and supports diagnostic tests for autoimmune diseases.

Some 98% of production is exported to more than 3,000 laboratories in 60 countries.

Supplying seven out of ten allergy laboratory tests worldwide, the company has remained the world leader in its field for more than 25 years.
 
Headquarters + Allergy
Phadia AB
P.O. Box 6460 SE-751 37 Uppsala Sweden