PerkinElmer has released 24 new AlphaLISA ''No Wash'' immunoassay kits for biomarker detection including non-human targets with four new mouse-specific kits.

The Alpha Donor bead (blue) is coated with streptavidin which captures the biotinylated antibody. The Acceptor bead (red) is coated with analyte-specific antibody.

The beads are brought into proximity through binding to the analyte.

When excited by laser at 680nm, the Alpha Donor bead releases singlet oxygen which travels to the nearby Acceptor bead where it induces emission of light.

AlphaLISA immunoassay kits use a proprietary bead-based technology and are an alternative to traditional enzyme-linked immunosorbent assay (ELISA).  The narrow and bright emission spectra of the Alpha technology makes AlphaLISA the a sensitive no-wash, high throughput assay for small molecules, large proteins and complex samples such as serum and plasma.

AlphaLISA immunoassay kits are said to be ideal for moderate-high throughput, precious samples, serum or lysates.

The AlphaLISA kits are for research use only, not for diagnostic procedures.

(SOURCE:reproduced)